Albendazole Tablets. Page 1170

Insert before other Tests.

Dissolution (2.5.2).

Apparatus No. 1,

Medium. 900 ml of 0.1 M hydrochloric acid,

Speed and time. 75 rpm and 30 minutes.

Withdraw a suitable volume of the medium and filter. Dilute 1.0 ml of filtrate to 50.0 with 0.1 M sodium hydroxide. Measure the absorbance of the resulting solution at the maximum at about 308 nm (2.4.7). Calculate the content of C12H15N3O2S in the medium taking 742 as the specific absorbance at 308 nm.

  1. D. Not less than 80 percent of the stated amount of C12H15N3O2S.

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