Reference Substances: Certain monographs require the use of a chemical reference substance or a biological reference preparation or a reference spectrum These are authentic specimens chosen and verified on the basis of their suitability for intended use as prescribed in the Pharmacopoeia and are not necessarily suitable in other circumstances. 

IP Reference Substances, abbreviated to IPRS (and referred to as RS in the individual monographs) are issued by the Indian Pharmacopoeia Commission (IPC). They are the official standards to be used in cases of arbitration. Secondary Standards (Working Standards) may be used for routine analysis, provided they are standardized at regular intervals against the Reference Substances

Biological Reference Substances, also abbreviated to IPRS and Standard Preparations of antibiotics are issued by agencies authorised by the IPC. They are standardized against the International Standards and Reference Preparations established by the World Health Organization (WHO). The potency of these preparations is expressed in International Units.  

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Price *New (With effected from - 01st May, 2017):
IPRS: Rs. 5000/-  per vial for Private Stakeholders and Rs. 2500/- per vial for Government Stakeholders

GST: 18%

Impurity: As per List (See Impurity Rate List please click)

(Demand Draft drawn in favour of "Indian Pharmacopoeia Commission"  payable at Ghaziabad)

The System of buying online IPRS has not started yet 

You can send the payment through RTGS/NEFT in below mentioned details.

Bank name- Bank of Baroda
Branch- Sanjay Nagar, Ghaziabad
A/c Name- Indian Pharmacopoeia Commission
A/c No.- 21860100013540
IFSC Code- BARB0SANGHA         0 = zero
Type of Account-Saving Account


  From 1st July, 2017 GST will be applicable on Indian Pharmacopoeia Reference Substance (IPRS), Impurity Substances, Tablets, Testing charges, PT Programme, Botanical Reference Standard

  GST Number for Indian Pharmacopoeia Commission

  IP Prednisone Tablet (Dissolution Apparatus Calibrator) is available at IPC, Ghaziabad

  List of IP Reference Substances available at IPC, Ghaziabad

  List of Impurities available at IPC, Ghaziabad  (273KB,  )

  List of Phytopharmaceutical Reference Substances (PRS) (278KB,  ) 

  IPRS Biologicals 

  Supply Order Form for IPRS and Impurity (207KB,  )

  Effective use of IPRS

  Protocol of IP Prednisone Tablet for Dissolution Apparatus Calibration


  IPRS and Impurity Standards Roadmap for 2016-17 (825KB,  ) 

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